Other causes or differential diagnoses for irritable bowel syndrome include.
As already indicated above, the diagnosis of IBS is not always easy. In turn, however, there are various other diagnoses that can cause pronounced and chronic intestinal complaints and should always be clarified.
1. SIBO = Small Intestinal Bowel Syndrome
In many patients with irritable bowel syndrome, the cause is small intestinal miscolonization (syn.: bacterial overgrowth syndrome). Small intestinal overgrowth occurs when bacteria from the large intestine migrate into the small intestine and now colonize it incorrectly. This can happen, for example, when there is increased gas formation in the large intestine, as is often the case when the environment in the intestine is disturbed.
2. Histamine intolerance
In histamine intolerance, there is an imbalance between the histamine produced in the organism and the ability to break it down to a sufficient extent. The cause can be, for example, an enzyme deficiency or increased histamine formation in the intestine. This typically leads to symptoms such as migraine, palpitations, flushing or urticaria (hives) – and also to abdominal complaints.
Likewise, various food intolerances such as frutose, lactose or gluten intolerance can lead to IBS symptoms and should always be considered.
3. Fungal or parasitic load
We deworm our pets regularly and immediately take countermeasures in case of mold in the house. But an intestinal fungal disease or parasite colonization in humans rarely receives attention and is usually not examined at all. But it is neither difficult nor costly: a stool sample is sufficient. Particularly with bad nourishing habits and/or weakened immune system fungi like also parasites have easy play and love the intestine with all its nutrients: Digestive problems are pre-programmed!
4. Exocrine pancreatic insufficiency
When there is pancreatic insufficiency, there is reduced secretion of digestive enzymes. The digestive enzymes normally enter the small intestine via the pancreatic duct and are essential for breaking down our food, especially fats and proteins. If the digestive enzymes are not sufficiently present (and this is not so rare), then the food reaches the large intestine undigested. And this can have a lasting effect on intestinal function, because if the food is not digested well, then fermentation and putrefaction processes occur more quickly and these favor dysbiosis. Pancreatic insufficiency can be easily detected by determining pancreatic elastase in the stool. If there is a deficiency, treatment is by substitution of the digestive enzymes.